产品货号：
Z11339
中文名称：
ARG2抗体
英文名称：
Anti-ARG2 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ARG2 Antibody |
| 指标别名 | ARG2;Arginase 2;mitochondrial;arginase;type II;Kidney type arginase;Non hepatic arginase;Type II arginase |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | ARG2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human Arg2(67-85aa DFGDLSFTPVPKDDLYNNL),different from the related mouse sequence by three amino acids and from the related rat sequence by two amino acids. |
| 实际分子量 | 38KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ARG2(arginase,type II) encodes a 355-amino acid polypeptide.Using Northern blotting and RT-PCR,Vockley et al.(1996) found that ARG2 is expressed as a 1.5-kb mRNA in a wide variety of tissues,with highest levels of expression in prostate,brain,and kidney.By PCR analysis of somatic cell hybrid panels,fluorescence in situ hybridization,and radiation hybrid analysis,the ARG2 gene is mapped to 14q24.1-q24.3.ARG2 may be inducible and may be essential in the regulation of nitric oxide synthesis by modulating local arginine concentrations.Gotoh et al.(1996) showed that ARG2 mRNA and nitric oxide synthase(NOS) mRNA were coinduced by lipopolysaccharide in a macrophage-like cell line.Arginase II has been implicated in the regulation of the arginine/ornithine concentrations in the cell.The mitochondrial location of ARG2 and its coinduction with ornithine aminotransferase and involvement with proline biosynthesis in lactating rat mammary gland had led to the inference that ARG2 is involved in biosynthetic functions,as opposed to the metabolic ones of the urea cycle. |
| Uniprot ID | P78540 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | arginase,type II |
| 蛋白名全称 | Arginase-2,mitochondrial |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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